Natural history of inflammatory bowel disease patients submitted to solid organ transplantation

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Natural history of inflammatory bowel disease patients submitted to solid organ transplantation.

Studies on the natural history of patients with inflammatory bowel disease (IBD) submitted to solid organ transplantation (SOT) reported contradictory results. Most studies report a more aggressive course of the intestinal disease after transplantation.1,2 There are factors which have been associated with the development of IBD “de novo” after transplantation, such as CMV infection (i.e., patie...

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Natural history of pancreatic involvement in paediatric inflammatory bowel disease.

BACKGROUND Few case reports describe the clinical features of pancreatic involvement in inflammatory bowel disease. AIM To investigate prevalence and disease course of inflammatory bowel disease children with pancreatitis and with exclusive hyperamylasemia and hyperlipasemia. METHODS We used a web-registry to retrospectively identify paediatric inflammatory bowel disease patients with hyper...

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Neonatal Presentation of Unremitting Inflammatory Bowel Disease

Very-early-onset inflammatory bowel disease (VEO-IBD) has a distinct phenotype and should be considered a specific entity. VEO-IBD presents with very severe clinical pictures and is frequently known by an indeterminate colitis whose clinical remission is unmanageable. This study examines the case of a neonate with VEO-IBD, not responding to medical and surgical treatment. A 7-day-old Iranian fe...

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Auto-antibodies in Patients with Inflammatory Bowel Disease Unclassified

Background: Inflammatory bowel disease unclassified (IBDU) is considered to be an aberrant immune response with loss of tolerance to many antigens. Objective: This paper tries to address whether there is any value to test for auto-antibodies in such patients. Methods: 60 patients with inflammatory bowel disease unclassified participated in the study. Auto-antibodies to nuclear antigen, intestin...

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Introduction to Solid Organ Transplantation

Organ transplantation has been the subject of ancient myths dating back to the twelfth century. The modern era of transplantation began in the early 1900s with the development of surgical techniques for constructing vascular anastomoses [ 1 ] leading to successful kidney transplantation in dogs in 1902 [ 2 ]. The fi rst series of human kidney transplants were performed in the Ukraine beginning ...

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ژورنال

عنوان ژورنال: Journal of Crohn's and Colitis

سال: 2013

ISSN: 1873-9946

DOI: 10.1016/j.crohns.2012.11.009